Currently, only cost optimization is supported. However, there are plans for a carbon-aware optimizer that aims to pick the 'greenest' VM for a specified job. To optimize for latency, you can manually specify regions in the job YAML file. For performance, VMs with the same resource specification are expected to have similar raw performance. Network latency should not impact simulation performance if the simulation does not need to communicate with your laptop. The size of the design spec file and the simulation duration will determine the impact of network latency during the upload.